Table 5.
Outcomes across VDZ versus non-biologic treated patients with anastomosis [with and without ostomy].
| Anastomosis with temporary ostomy | Anastomosis, no ostomy | |||||||
|---|---|---|---|---|---|---|---|---|
| [ALL] | No bio | VDZ | p | [ALL] | No bio | VDZ | p | |
| N = 137 | N = 122 | N = 15 | N = 328 | N = 318 | N = 10 | |||
| Intra-abdominal sepsis | 18 [13.1%] | 15 [12.3%] | 3 [20.0%] | 0.418 | 29 [8.90%] | 29 [9.18%] | 0 [0.00%] | 0.609 |
| Intra-abdominal abscess | 11 [8.03%] | 8 [6.56%] | 3 [20.0%] | 0.103 | 24 [7.32%] | 24 [7.55%] | 0 [0.00%] | 1.000 |
| Leak | 9 [6.57%] | 9 [7.38%] | 0 [0.00%] | 0.597 | 9 [2.76%] | 9 [2.85%] | 0 [0.00%] | 1.000 |
| Superficial wound infection | 12 [8.76%] | 12 [9.84%] | 0 [0.00%] | 0.361 | 19 [5.79%] | 18 [5.66%] | 1 [10.0%] | 0.454 |
| 90-day mortality | 0 [0.00%] | 0 [0.00%] | 0 [0.00%] | . | 0 [0.00%] | 0 [0.00%] | 0 [0.00%] | . |
| 90-day ileus | 48 [35.0%] | 42 [34.4%] | 6 [40.0%] | 0.888 | 85 [25.9%] | 83 [26.1%] | 2 [20.0%] | 1.000 |
| Return OR 90 days | 19 [13.9%] | 17 [13.9%] | 2 [13.3%] | 1.000 | 13 [3.96%] | 13 [4.09%] | 0 [0.00%] | 1.000 |
| Readmit 90 days | 43 [31.4%] | 37 [30.3%] | 6 [40.0%] | 0.556 | 42 [12.8%] | 41 [12.9%] | 1 [10.0%] | 1.000 |
| Any infectious complication | 43 [31.4%] | 39 [32.0%] | 4 [26.7%] | 0.776 | 60 [18.3%] | 58 [18.2%] | 2 [20.0%] | 1.000 |
| Non-surgical infectious complication | 21 [15.3%] | 20 [16.4%] | 1 [6.67%] | 0.467 | 25 [7.65%] | 24 [7.57%] | 1 [10.0%] | 0.554 |
| Surgical infectious complication | 26 [19.1%] | 23 [19.0%] | 3 [20.0%] | 1.000 | 44 [13.4%] | 43 [13.5%] | 1 [10.0%] | 1.000 |
VDZ, vedolizumab; No bio, no biologic treatment; OR, operating room.