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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Drug Metab Rev. 2020 Oct 14;52(4):472–500. doi: 10.1080/03602532.2020.1832112

Figure 2. The Rumack-Matthew nomogram.

Figure 2.

When measured between 4 and 24 hours after APAP overdose, values above the dashed line (Rumack-Matthew line) are likely to result in hepatotoxicity, values between the dashed line and the solid line (Treatment line) may or may not lead to hepatotoxicity, and values below the solid line are unlikely to cause hepatotoxicity. All patients with values above the Treatment line should receive NAC.