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. 2021 Sep 4;12:819–826. doi: 10.2147/JBM.S321372

Table 1.

Hospital-Based Clinical Staging System for COVID-19 to Assess Disease Severity

Stage Clinical Presentation Characteristic Features
Stage A Asymptomatic Patients with no signs or symptoms of infection
Stage B Mild Infection Upper respiratory tract infection symptoms and other mild symptoms (including fever and gastrointestinal symptoms) without evidence of pneumonia
Stage C Moderate Infection Patients with hypoxia with oxygen saturation less than 93% at rest or presence of pneumonia not requiring ICU admission
Stage D Severe Infection Pneumonia requiring ICU admission or any of the following:
1. Respiratory rate of 30 breaths/min
2. Arterial oxygen partial pressure to fractional inspiratory oxygen ratio (PaO2/FiO2) less than 300
3. More than 50% lung involvement on imaging within 24–48 hours
4. Critical respiratory failure requiring mechanical ventilation, septic shock, or multi-organ dysfunction