Table 3.
Proposed weight-based and age-based dosing of primaquine
Weight-based dosing | Age-based dosing | ||||
---|---|---|---|---|---|
Bodyweight (kg) | Primaquine daily dosea (mg) | Primaquine daily dosea (mg/kg/day) | Age (years) | Primaquine daily dosea (mg) | Primaquine daily dosea (mg/kg/day) |
5–7 | 5 | 0.71–1.00 | < 1b | 5 | 0.43–1.00 |
8–16 | 7.5 | 0.47–0.94 | 1–5 | 7.5 | 0.34–1.25 |
17–40 | 15 | 0.38–0.88 | 6–14 | 15 | 0.28–1.30 |
41–80 | 30 | 0.37–0.73 | ≥ 15 | 30 | 0.35–1.11 |
81–100 | 45 | 0.45–0.56 |
aDaily dose based on a 14-day regimen
bThe lowest age-band is proposed for infants is 6 months to 11 months of age