Supplementary Table 3.
Predictors for No or Only a Low Humoral Immune Response in LT Recipients After Second SARS-CoV-2 Vaccination Based on the Trimer Immunoassay (Cutoff 33.8 BAU/mL)
| Anti-S trimer, BAU/mL n, % within group |
P | Median anti-S trimer (IQR), BAU/mL | ||
|---|---|---|---|---|
| < 33.8 | ≥ 33.8 | |||
| Age >65 y | 21 (80.8) | 5 (19.2) | < .001 | 10 (5–41) |
| Age ≤65 y | 44 (40.4) | 65 (59.6) | 294 (24–1245) | |
| Arterial hypertension | 48 (57.8) | 35 (42.2) | .004 | 56 (5–732) |
| No arterial hypertension | 17 (32.7) | 48 (57.8) | 394 (27–1693) | |
| CNI mono | 8 (24.2) | 25 (75.8) | .002 | 753 (137–2020) |
| CNI + other IS | 56 (55.4) | 45 (44.6) | 72 (5–664) | |
| B-lymphocytes <80/μl | 13 (68.4) | 6 (31.6) | .044 | 18 (5–471) |
| B-lymphocytes ≥80/μl | 13 (39.4) | 20 (60.6) | 407 (27–1145) | |
Note: Boldface P values indicate statistical significance.
Anti-S trimer, Anti-SARS-CoV-2 antibodies in DiaSorin LIAISON immunoassay; BAU, binding antibody units; CNI, calcineurin inhibitor; IQR, interquartile range; IS, immunosuppression; LT, liver transplant; SARS-CoV-2, severe acute respiratory syndrome coronavirus type 2.