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. 2021 Sep 9;137:104857. doi: 10.1016/j.compbiomed.2021.104857

Table 4.

Detailed results (%) with a 95% confidence interval of five models. The numbers in bold black font represent the best classification result in the corresponding category. Note that the p-values are calculated between DenseANet and Baseline+ARL.

Models Category Acc AUC Se Sp Pr F1
Results of 2D slices ResNet101 CP 91.84 ± 1.21 97.64 ± 0.47 91.84 ± 1.05 91.85 ± 1.23 92.00 ± 1.37 91.72 ± 0.95
NCP 92.63 ± 0.92 97.80 ± 0.43 88.04 ± 1.58 94.54 ± 0.74 86.98 ± 1.74 87.31 ± 1.49
Normal 98.89 ± 0.27 99.71 ± 0.11 96.59 ± 0.37 99.47 ± 0.19 97.89 ± 0.55 97.03 ± 0.46
ResNet101+ARL CP 92.99 ± 1.04 97.96 ± 0.35 91.72 ± 1.70 94.28 ± 0.76 94.25 ± 0.62 92.66 ± 0.82
NCP 93.63 ± 1.19 98.01 ± 0.23 92.39 ± 1.21 94.14 ± 0.45 86.73 ± 1.29 89.37 ± 1.66
Normal 99.08 ± 0.21 99.47 ± 0.17 96.33 ± 0.85 99.77 ± 0.08 99.06 ± 0.16 97.48 ± 0.58
Baseline CP 94.07 ± 0.87 98.28 ± 0.28 97.09 ± 0.65 90.99 ± 1.58 91.67 ± 1.07 94.03 ± 0.89
NCP 94.90 ± 0.49 98.23 ± 0.31 86.61 ± 1.18 98.34 ± 0.31 95.59 ± 0.65 90.65 ± 1.07
Normal 98.95 ± 0.22 99.63 ± 0.14 96.81 ± 0.64 99.49 ± 0.18 97.95 ± 0.52 97.14 ± 0.41
Baseline+ARL CP 93.50 ± 0.89 98.35 ± 0.20 92.08 ± 1.22 94.95 ± 0.53 94.91 ± 0.54 93.27 ± 0.73
NCP 94.04 ± 0.72 98.40 ± 0.21 92.96 ± 0.97 94.48 ± 0.62 87.48 ± 1.17 90.04 ± 1.25
Normal 99.03 ± 0.14 99.73 ± 0.07 96.78 ± 0.52 99.60 ± 0.29 98.39 ± 0.23 97.35 ± 0.46
DenseANet CP 94.81 ± 0.39 98.38 ± 0.24 98.25 ± 0.21 91.02 ± 0.85 93.07 ± 0.71 94.66 ± 0.56
NCP 95.67 ± 0.32 98.61 ± 0.12 87.19 ± 1.68 98.61 ± 0.33 95.83 ± 0.65 91.41 ± 0.71
Normal 98.87 ± 0.16 99.57 ± 0.14 95.44 ± 0.81 99.74 ± 0.13 99.76 ± 0.14 97.53 ± 0.39
p-value CP 0.003 0.742 6.35e-7 1.08e-4 0.002 0.007
NCP 0.007 0.461 2.56e-5 5.38e-7 1.08e-7 0.012
Normal
0.477
0.215
0.035
0.269
0.014
0.083
Results of patients ResNet101 CP 91.05 ± 1.48 97.07 ± 0.52 90.55 ± 1.17 91.32 ± 1.19 84.65 ± 2.09 87.25 ± 2.17
NCP 92.77 ± 1.09 97.63 ± 0.64 83.43 ± 1.88 96.60 ± 0.63 90.97 ± 1.32 86.91 ± 2.06
Normal 98.28 ± 0.33 99.56 ± 0.13 97.63 ± 0.52 98.65 ± 0.38 97.63 ± 0.44 97.47 ± 0.42
ResNet101+ARL CP 92.08 ± 0.96 97.55 ± 0.51 91.54 ± 1.29 92.37 ± 1.24 86.38 ± 2.17 88.65 ± 1.85
NCP 93.80 ± 0.84 97.90 ± 0.32 86.39 ± 1.14 96.84 ± 0.58 91.82 ± 1.17 88.92 ± 1.75
Normal 98.28 ± 0.27 99.71 ± 0.15 97.16 ± 0.43 98.92 ± 0.39 98.09 ± 0.36 97.41 ± 0.49
Baseline CP 92.08 ± 1.21 98.12 ± 0.35 96.02 ± 0.61 90.00 ± 1.23 83.55 ± 1.75 89.15 ± 1.25
NCP 93.63 ± 1.05 98.43 ± 0.47 80.47 ± 2.03 99.03 ± 0.20 97.14 ± 0.49 87.96 ± 1.19
Normal 98.45 ± 0.24 99.53 ± 0.28 97.63 ± 0.34 98.92 ± 0.14 98.10 ± 0.38 97.64 ± 0.42
Baseline+ARL CP 93.12 ± 0.71 97.80 ± 0.46 90.55 ± 0.91 94.47 ± 0.90 89.66 ± 1.26 90.04 ± 1.08
NCP 93.80 ± 0.94 98.08 ± 0.32 88.17 ± 0.97 96.12 ± 0.57 90.30 ± 1.19 89.13 ± 1.12
Normal 98.62 ± 0.33 99.64 ± 0.09 98.58 ± 0.21 98.65 ± 0.17 97.65 ± 0.32 97.91 ± 0.63
DenseANet CP 94.11 ± 0.25 98.81 ± 0.17 98.10 ± 0.33 91.99 ± 0.32 86.68 ± 0.50 92.03 ± 0.32
NCP 94.86 ± 0.33 98.13 ± 0.11 82.40 ± 1.28 99.06 ± 0.24 96.71 ± 0.82 88.98 ± 0.76
Normal 99.20 ± 0.14 99.74 ± 0.08 98.00 ± 0.36 100.00 ± 0.00 100.00 ± 0.00 98.99 ± 0.18
p-value CP 0.012 0.003 4.95e-7 1.75e-4 0.001 0.003
NCP 0.004 0.098 9.17e-6 1.68e-5 9.22e-8 0.218
Normal 0.021 0.273 0.047 0.013 0.004 0.016