Table 5.
Results of NAS.
| Parameter | Groups | H | P Value | ||
|---|---|---|---|---|---|
| Negative Control (n=4) | NASH (n=4) | NASH + ADF (n=4) | |||
| Ballooning | 0.00 (0.00–0.00) A |
2.00 (1.00–2.00) B |
1.00 (1.00–1.00) B |
47.791 | <0.0005 |
| Steatosis | 0.00 (0.00–1.00) A |
3.00 (2.00–3.00) B |
1.00 (1.00–2.00) C |
49.692 | <0.0005 |
| Inflammation | 0.00 (0.00–0.00) A |
1.00 (1.00–3.00) B |
1.00 (0.00–2.00) C |
37.644 | <0.0005 |
| NAS | 0.00 (0.00–1.00) A |
6.00 (3.00–7.00) B |
3.00 (2.00–4.00) C |
52.354 | <0.0005 |
Data are expressed as median (interquartile range). P value by Kruskal–Wallis H-test (different letters = significant difference); significant p value is considered when ≤0.05. Abbreviations: NASH, non-alcoholic steatohepatitis; ADF, alternate-day fasting; NAS, NAFLD activity scoring.