Table 7.
Relative Quantification of the Studied Genes in Rat Liver Tissues From the Three Studied Groups.
| Parameter | Group | F Value | P Value | Partial eta Squared | ||
|---|---|---|---|---|---|---|
| Negative Control (n=4) | NASH (n=4) | NASH With ADF (n=4) | ||||
| ACACA | 0.93 ± 0.56 A |
5.64 ± 1.04 B |
1.61 ± 0.71 A |
10.187 | 0.005 | 0.694 |
| PPAR-γ | 0.84 ± 0.39 A |
2.94 ± 0.60 B |
0.88 ± 0.44 A |
6.111 | 0.021 | 0.576 |
| PPAR-α | 0.61 ± 0.18 A |
1.70 ± 0.58 A |
0.92 ± 0.30 A |
2.035 | 0.187 | 0.311 |
| Caspase-3 | 1.06 ± 0.21 A |
4.04 ± 0.28 B |
2.01 ± 0.25 C |
38.139 | <0.0005 | 0.894 |
| P53 | 0.95 ± 0.37 A |
2.29 ± 0.15 B |
0.82 ± 0.38 A |
6.55 | 0.018 | 0.593 |
| Bcl-2 | 0.92 ± 0.44 A |
1.77 ± 0.17 A |
1.42 ± 0.57 A |
0.994 | 0.407 | 0.181 |
| COX2 | 0.48 ± 0.20 A |
4.44 ± 1.16 B |
0.60 ± 0.35 A |
10.011 | 0.005 | 0.690 |
Data are expressed as mean ± SE. P value by one-way ANOVA, followed by post hoc test “Tukey adjustment” (different letters = statistically significant difference); p value is considered significant if it is ≤0.05 and demonstrated in boldface. Abbreviations: NASH, non-alcoholic steatohepatitis; ADF, alternate-day fasting, ACACA, acetyl CoA carboxylase; PPAR-γ, peroxisome proliferator-activated receptor γ; PPAR-α, peroxisome proliferator-activated receptor α; p53, tumor protein p53; Bcl-2, B-cell lymphoma 2; COX-2, cyclo-oxygenase 2.