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. 2021 Sep 9;19:200. doi: 10.1186/s12915-021-01118-w

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — Discrimination of embryo quality based on the metabolomic indicators with clinical parameters. Discrimination is based on 2 lines of statistical evidence. The upper panel shows the ROC analysis, and the lower panel shows the averages of feature importance in the RF model. A total of 5 subgroups of the clinical parameters are selected: A the patients aged < 35, B the patients aged ≥ 35, C the patients who received the long protocol, D the patients who received the ultralong protocol, and E the patients who received the GnRH-ant protocol. The X-axis and Y-axis represent the same variables as in Fig. 3D and E