Figure 1.

Methods of investigating the effects of variation in CLOCK in interaction with childhood adversities and recent life events on lifetime and current depression: study population, quality control steps, and statistical analyses. RLE, recent life events; CHA, Childhood adversities; BSI-Dep, Brief Symptom Inventory depression score; ADD, additive model; DOM, dominant model; REC, recessive model; HWE, Hardy-Weinberg Equilibrium; MR, missingness rate; MAF, minor allele frequency; DEP, lifetime depression; FDRQ, False Discovery Rate Q value.