Oncolytic activity in ovarian cancer xenograft models using immunodeficient NSG mice. (A). Representative mouse in each group of the NSG/Kuramochi model imaged on day 1 and day 50. (B). Firefly luciferase intensity of NSG/Kuramochi groups on day 1 and day 50. *** p = 0.0004, CRAd group vs control group, ns, no statistical significance, n = 5. (C). Survival curve of NSG/Kuramochi model. ** p = 0.0097, n = 5. (D). Survival curve of NSG/OVCAR4 xenograft model with n = 5 in each group. * p = 0.0204, control vs. CRAd; ** p = 0.0028, control vs CRAd-infected cells, * p = 0.0326, CRAd vs. CRAd-infected cells.