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. 2021 Sep 6;9:e12117. doi: 10.7717/peerj.12117

Figure 1. Synthetic PPIN1.

Figure 1

The PPIN consists of 33 nodes and 53 edges. Nodes 1, 24 are the essential spreaders. Node 1 connects the four densely connected modules of the PPIN, which turns this node to stand in the first position having the highest spreadability index. Node 24 holds the second position for the spreadability index. Node 24 is one of the most densely connected modules itself despite getting isolated from the main PPIN module of node 1.