Table 4. Computation of LAC of synthetic Fig. 1 and computation of spreadability rate of selected top 10 spreader nodes by the SIS model.

Rank	Proteins	Local average centrality	Sum of SIS spreadability rate of top 10 nodes
1	21	2.4	2.19
2	9	2
3	22	2
4	8	2
5	11	2
6	12	2
7	13	2
8	2	1.6
9	23	1.6
10	7	1.5
11	3	1.5	–
12	5	1.5
13	16	1.33
14	15	1.33
15	20	1.33
16	32	1.33
17	19	1
18	10	1
19	31	1
20	33	1
21	24	0.57
22	4	0.5
23	17	0.5
24	1	0
25	14	0
26	18	0
27	6	0
28	28	0
29	29	0
30	30	0
31	25	0
32	26	0
33	27	0