Table 7. Computation of spreadability index of SARS-CoV PPIN and computation of spreadability rate of selected top 6 spreader nodes by the SIS model.
| Rank | Proteins | E Si | Edge ratio | Neighborhood density | Node weight | Spreadability index | SIS spreadability rate of top 6 nodes | Sum of SIS spreadability rate of top 6 nodes | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | M | 7 | 3 | 2.0 | 3.845 | 3.4 | 11.090 | 1 | 2.935 |
| 2 | S | 6 | 3 | 1.75 | 4.047 | 3.2 | 10.283 | 0.2 | |
| 3 | ORF8AB | 7 | 3 | 2.0 | 1.785 | 4.0 | 7.5714 | 1 | |
| 4 | ORF8B | 5 | 5 | 1.0 | 3.464 | 3.8 | 7.2642 | 0.2 | |
| 5 | E | 7 | 3 | 2.0 | 1.428 | 4.0 | 6.8571 | 0.25 | |
| 6 | ORF3A | 2 | 8 | 0.333 | 9.249 | 3.428 | 6.5119 | 0.285 | |
| 7 | ORF7A | 2 | 8 | 0.333 | 9.25 | 3.428 | 6.5119 | – | – |
| 8 | ORF8A | 3 | 0 | 4.0 | 0.0 | 2.0 | 2 | ||
| 9 | N | 3 | 0 | 4.0 | 0.0 | 2.0 | 2 |