Table 1.
Characteristics of the study group.
| Study Group Data | Control (n = 69) | Breast Cancer (n = 171) | p Value |
|---|---|---|---|
| Clinical data | |||
| Age | 43 (38–54) | 44 (37–50) | n.s |
| Children | 2 (1–2) | 2 (1–2) | n.s |
| Age of Menarche | 12 (11–13) | 12 (12–14) | n.s |
| Menopause (Yes, %) | 30.3 | 20.2 | n.s |
| BMI (Kg/m2) | 24.02 (22.20–28.13) | 25,07 (22.72–28.36) | n.s |
| Biochemical data | |||
| Cholesterol (mg/dl) | 194.18 ± 28.31 | 208.06 ± 31.40 | <0.005 |
| Apo A1 (mg/dl) | 147.22 ± 28.66 | 147.64 ± 27.34 | n.s |
| Apo B100 (mg/dl) | 91 (78–104) | 101 (85–118) | <0.05 |
| Triglycerides (mg/dl) | 76.55 (56.83–98.74) | 86.73 (67.69–120.16) | <0.005 |
| FABP4 (ng/mL) | 13.085 (8.73–18.05) | 17.53 (13.15–23.33) | <0.001 |
| FABP5 (ng/mL) | 6.12 (5.44–7.91) | 7.00 (5.26–9.04) | n.s |
| CETP activity (pmol/µL) | 47.87 (26.95–69.54) | 51.98 (31.71–76.43) | n.s |
| CETP protein (ng/µL) | 596.51 ± 163.39 | 579.63 ± 155.76 | n.s |
| CD36 (pg/mL) | 908.67 (762.00–1037.56) | 897.00 (763.37–997.56) | n.s |
Data are expressed as medians (IQR) for non-normally distributed data, means ± SD for normally distributed data, or percentages for categorical variables. The statistical tests used were Student’s t test (for data that were normally distributed), Mann–Whitney U test (for data that were not normally distributed), or chi-square tests (for data gathered as categorical variables). Abbreviations: ApoAI, apolipoprotein AI; ApoB100, apolipoprotein B100; BMI, body mass index; CETP, cholesteryl ester transfer protein; CD36, cluster of differentiation 36; IQR, interquartile range; SD, standard deviation. Baseline measurements for the study group. Data are expressed as means ± SD for normally distributed data, medians (IQR) for non-normally distributed data, and percentages for categorical variables. Student’s t test was used for data that were normally distributed, Mann–Whitney U test was performed for data that were not normally distributed, and chi-square tests were used for categorical variables. Abbreviations: ApoAI, apolipoprotein AI; ApoB100, apolipoprotein B100; BMI, body mass index; FABP4, fatty acid binging protein 4; FABP5, fatty acid binging protein 5; CETP, cholesteryl ester transfer protein; CD36, cluster of differentiation 36; IQR, interquartile range; SD, standard deviation.