Figure A1.

A systematic search was carried out through an online search in PubMed using the MeSH database. Additional relevant references from the obtained literature were reviewed. With exception of case reports, clinical trials and letters to the editor, we included all English-written studies based on original data for title and abstract screening, regardless of year of publication. As no articles directly assessed the topic of our review, our inclusion and exclusion criteria were dynamic, as new ideas emerged. A PRISMA flowchart was made including reasons for exclusion of the literature.