Figure 2.

Class discovery associated with the SLN metastatic status. The analysis was performed using the 50 miRNAs with the largest coefficient of variation based on trimmed mean of M-values (TMM counts). (A) Heat map and unsupervised hierarchical clustering. Each row represents one miRNA and each column represents one sample. The color represents the relative expression level of a miRNA across all samples. The color scale shows the expression level above (red) or below (green) the mean. (B) Principal Component Analysis (PCA) of samples according to the SLN metastatic status of patients.