Table 1.
Baseline characteristics of aortic valves obtained from patients.
| Variable | Non-CAVD (n = 12) | CAVD (n = 11) | p |
|---|---|---|---|
| Age, years | 62 (58–66) | 72 (65–77) | <0.01 |
| BMI, kg/m2 | 26 (24–27) | 23 (21–25) | 0.02 |
| Male, n (%) | 10 (83) | 10 (91) | NS |
| Smoking status, n (%) | 2 (17) | 3 (27) | NS |
| Alcohol consumption, n (%) | 1 (8) | 3 (27) | NS |
| Hypertension, n (%) | 8 (67) | 7 (64) | NS |
| CHD, n (%) | 12 (100) | 11 (100) | NS |
| DM, n (%) | 3 (25) | 0 (0) | NS |
| SBP, mmHg | 141 (129–156) | 131 (115–143) | NS |
| DBP, mmHg | 80 (71–88) | 72 (58–78) | NS |
| Fasting glucose, mmol/L | 4.96 (4.12–5.94) | 5.40 (4.88–5.88) | NS |
| HbA1c, % | 6.5 (5.8–7.0) | 5.7 (5.5–6.0) | 0.03 |
| TG, mmol/L | 1.77 (1.06–2.48) | 1.35 (0.69–1.96) | NS |
| TC, mmol/L | 4.07 (3.03–4.81) | 4.59 (3.37–5.55) | NS |
| HDL-c, mmol/L | 0.88 (0.67–1.06) | 1.08 (0.94–1.26) | 0.04 |
| LDL-C, mmol/L | 2.55 (1.60–3.44) | 2.78 (1.77–3.17) | NS |
| Lp(a), g/L | 0.21 (0.07–0.30) | 0.30 (0.10–0.31) | NS |
| BUN, mmol/L | 5.17 (4.33–5.80) | 6.55 (4.20–8.20) | NS |
| SCr, μmol/L | 83.08 (78–91) | 104.55 (76.00–123.00) | NS |
| eGFR, ml/min | 84.18 (81.25–89.88) | 67.89 (52.70–88.60) | NS |
| Cystatin, mg/L | 1.10 (0.89–1.20) | 1.39 (1.14–1.72) | 0.04 |
| Ca, mmol/L | 2.22 (2.13–2.32) | 2.18 (2.07–2.31) | NS |
| P, mmol/L | 1.17 (1.09–1.29) | 0.99 (0.85–1.14) | 0.02 |
| Aortic valve area, cm2 | – | 0.74 ± 0.07 | – |
| Aortic mean gradient, mmHg | – | 47 ± 3 | – |
| Glucose lowering therapy, n (%) | 3 (25) | 0 (0) | NS |
| Statins, n (%) | 11 (92) | 11 (100) | NS |
Continuous variables are presented as the median (25th−75th percentile), and categorical variables are expressed as n (%). For continuous variables, Mann-Whitney U-tests were performed to assess differences. Differences in proportions were analyzed by 2 × 2 chi-square tests.