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. 2021 Aug 26;8:709741. doi: 10.3389/fcvm.2021.709741

Table 3.

Multivariable regression analysis for the risk of CAVD.

Variable B S.E. OR (95% CI) P
Model 1 Age 0.227 0.023 1.255 (1.199–1.313) <0.001
Fasting glucose −0.193 0.082 0.824 (0.702–0.968) 0.018
HbA1c 0.433 0.14 1.542 (1.171–2.031) 0.002
HDL −1.954 0.582 0.142 (0.045–0.443) 0.001
BUN 0.239 0.106 1.270 (1.032–1.563) 0.024
GLP-1 −0.118 0.027 0.889 (0.844–0.936) <0.001
Constant −14.442 1.831 <0.001
Model 2 Age 0.235 0.024 1.265 (1.207–1.325) <0.001
Fasting glucose −0.21 0.083 0.810(0.689–0.953) 0.011
HbA1c 0.422 0.142 1.525 (1.154–2.016) 0.003
HDL −2.027 0.597 0.132 (0.041–0.424) 0.001
BUN 0.214 0.107 1.239 (1.005–1.527) 0.045
GLP-1a <0.001
GLP-1a (8.69–12.31) −0.201 0.418 0.818 (0.361–1.855) 0.631
GLP-1a (12.32–16.73) −0.821 0.436 0.440 (0.187–1.034) 0.06
GLP-1a (16.74–39.37) −2.162 0.474 0.115 (0.045–0.291) <0.001
Constant −15.333 1.905 <0.001

Variable(s) entered in Model 1: Age, Male, Body mass index, Active smoker, Alcohol, Hypertension, Systolic blood pressure, Diastolic blood pressure, Diabetes, Fasting glucose, HbA1c, Coronary heart disease, Triglycerides, Total cholesterol, LDL, HDL, Lipoprotein(a), γ-glutamyl transpeptidase, Blood urea nitrogen, Creatinine, eGFR (CKD-EPI) and GLP-1. GLP-1a was transformed by dividing GLP-1 into quartiles. GLP-1a was a categorical variable in the model, with the lowest quartile (0.050–8.785) as a reference category. Variable(s) entered in Model 2: Age, Male, Body mass index, Active smoker, Alcohol, Hypertension, Systolic blood pressure, Diastolic blood pressure, Diabetes, Fasting glucose, HbA1c, Coronary heart disease, Triglycerides, Total cholesterol, LDL, HDL, Lipoprotein(a), γ-glutamyl transpeptidase, Blood urea nitrogen, Creatinine, eGFR (CKD-EPI), GLP-1a. B: unstandardized B coefficient.