Figure 5.
P-A regulates expression of IL-6, IL-10, and TNF-α through NF-кB and JAK/SATA pathways. (a) The expression of p-NF-кB p65 protein in HUVEC damage model. (1) cell control; (2) model; (3) NaHS; (4) P-A; (5) PDTC + NaHS; (6) PDTC + P-A. * P < 0.05 ** P < 0.01 vs model; # P < 0.05 ## P < 0.01 vs P-A; ⊿ P < 0.05 vs NaHS. Mean ± SD, n = 3. (b) The expression of p-JAK2 protein in the HUVEC damage model. (1) cell control; (2) model; (3) NaHS; (4) P-A; (5) AG490 + NaHS; 6: AG490 + P-A. (c) The expression of p-STAT3 protein in the HUVEC damage model. (1) cell control; (2) model; (3) NaHS; (4) P-A; (5) AG490 + NaHS; 6: AG490 + P-A. ** P < 0.01 vs model; ## P < 0.01 vs P-A; ⊿⊿ P < 0.01 vs NaHS. Mean ± SD, n = 3.