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. 2021 Sep 9;18(9):e1003751. doi: 10.1371/journal.pmed.1003751

Table 1. Characteristics of 3,227 Avon Longitudinal Study of Parents and Children Generation 1 offspring eligible for analyses.

Characteristics Overall (N = 3,227) Males (N = 1,257) Females (N = 1,970)
N Percent (N) or mean (SD) N Percent (N) or mean (SD) N Percent (N) or mean (SD)
Non-white ethnicity 3,227 3.9% (126) 1,257 3.7% (47) 1,970 4.0% (79)
Maternal education is degree 3,227 21.0% (676) 1,257 22.4% (282) 1,970 20.0% (394)
Age (y) at peak height velocity 2,924 12.4 (1.2) 1,155 13.5 (0.9) 1,769 11.8 (0.8)
Smoking at 25 y 3,191 1,240 1,951
    Never 36.1% (1,153) 35.4% (439) 36.6% (714)
    Less than weekly 58.3% (1,859) 57.6% (714) 58.7% (1,145)
    Every week 5.6% (179) 7.0% (87) 4.7% (92)
Alcohol consumption at 25 y 3,123 1,209 1,914
    Never/monthly/less than monthly 24.0% (748) 17.6% (213) 28.0% (535)
    2 to 4 times per month 38.5% (1,202) 36.6% (443) 39.7% (759)
    2 or more times per week 37.6% (1,173) 45.7% (553) 32.4% (620)
Total limb lean mass index (kg/m2) at 25 y 3,119 7.2 (1.3) 1,222 8.2 (1.1) 1,897 6.5 (0.9)
Arm lean mass index (kg/m2) at 25 y 3,119 1.7 (0.5) 1,222 2.2 (0.4) 1,897 1.5 (0.2)
Leg lean mass index (kg/m2) at 25 y 3,119 5.4 (0.9) 1,222 6.0 (0.8) 1,897 5.1 (0.7)
Maximum grip strength (lb/in2) at 25 y 1,964 14.1 (3.9) 771 17.4 (3.7) 1,193 12.1 (2.3)
Relative grip strength (lb/in2/kg) at 25 y 1,951 0.2 (0.1) 768 0.2 (0.1) 1,183 0.2 (0.04)
Total fat mass index (kg/m2) at 25 y 3,119 7.9 (3.7) 1,222 6.3 (3.0) 1,897 9.0 (3.8)
Changes from childhood to young adulthood, 10 to 25 y
Total limb lean mass index (kg/m2) 2,808 1.8 (1.0) 1,102 2.6 (0.9) 1,706 1.3 (0.7)
Arm lean mass index (kg/m2) 2,808 0.6 (0.4) 1,102 0.9 (0.3) 1,706 0.3 (0.2)
Leg lean mass index (kg/m2) 2,808 1.2 (0.7) 1,102 1.6 (0.7) 1,706 1.0 (0.6)
Maximum grip strength (SD)* 1,739 −0.001 (1.1) 681 −0.004 (1.1) 1,058 0.001 (1.1)
Relative grip strength (SD)* 1,727 −0.04 (1.0) 678 −0.01 (1.0) 1,049 −0.1 (1.0)
Total fat mass index (kg/m2) 2,808 3.6 (3.0) 1,102 2.6 (2.4) 1,706 4.2 (3.1)
Changes in childhood, 10 to 13 y
Total limb lean mass index (kg/m2) 2,565 1.0 (0.6) 1,017 1.3 (0.6) 1,548 0.7 (0.4)
Arm lean mass index (kg/m2) 2,565 0.3 (0.2) 1,017 0.4 (0.2) 1,548 0.2 (0.1)
Leg lean mass index (kg/m2) 2,565 0.7 (0.4) 1,017 1.0 (0.4) 1,548 0.5 (0.3)
Total fat mass index (kg/m2) 2,565 0.9 (1.7) 1,017 0.3 (1.6) 1,548 1.3 (1.6)
Changes in adolescence, 13 to 18 y
Total limb lean mass index (kg/m2) 2,404 0.3 (0.6) 934 0.8 (0.7) 1,470 −0.02 (0.4)
Arm lean mass index (kg/m2) 2,404 0.2 (0.2) 934 0.4 (0.2) 1,470 0.1 (0.1)
Leg lean mass index (kg/m2) 2,404 0.1 (0.5) 934 0.3 (0.5) 1,470 −0.1 (0.3)
Total fat mass index (kg/m2) 2,404 1.1 (2.0) 934 0.3 (1.9) 1,470 1.6 (1.9)
Changes in young adulthood, 18 to 25 y
Total limb lean mass index (kg/m2) 2,543 0.5 (0.7) 983 0.4 (0.8) 1,560 0.6 (0.7)
Arm lean mass index (kg/m2) 2,543 0.1 (0.2) 983 0.1 (0.3) 1,560 0.03 (0.2)
Leg lean mass index (kg/m2) 2,543 0.5 (0.6) 983 0.3 (0.6) 1,560 0.6 (0.6)
Total fat mass index (kg/m2) 2,543 1.6 (2.4) 983 2.2 (2.1) 1,560 1.3 (2.5)

Described are those with data on change in at least 1 lean, grip, or fat measure across any occasion and covariates used for those models, and at least 1 cardiometabolic trait at 25 y.

*Change is from age 12 y to 25 y and is based on difference in SD units, given different original measurement units between occasions.