Table 2.

Patterns of Illness Associated with Primary Immunodeficiency Diseases

Disorder	Illnesses
	Infection	Other
Antibody	Sinopulmonary (pyogenic bacteria, viruses)	Autoimmune disease (auto antibodies, inflammatory bowel disease)
	Gastrointestinal (enterovirus, giardia)
Cell-mediated immunity	Wide range of microorganisms, including opportunistic pathogens
	Pneumonia, (pyogenic bacteria, Pneumocystis jirovecii, viruses)
	Gastrointestinal (viruses)
	Skin, mucous membranes (fungi)
Complement	Sepsis and other blood-borne (streptococci, pneumococci, neisseria)	Autoimmune disease (systemic lupus erythematosus, glomerulonephritis)
Phagocytes	Skin, reticuloendothelial system (staphylococcus, enteric bacteria, fungi, mycobacteria)