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Charts showing the quantity of 85B mRNA detected at each time point as a percentage of that present in parallel control cultures in the absence of either INH or RIF. Drugs were added to cultures of M. tuberculosis at time zero. Cultures were exposed to either 0.2 μg of INH per ml (•) or 1 μg of RIF per ml (▴). (A) INH- and RIF-sensitive strain ATCC 27294; (B) INH-resistant strain ATCC 33823; (C) RIF-resistant strain ATCC 35838.
