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. 2021 Aug 26;12:666106. doi: 10.3389/fgene.2021.666106

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Copyright © 2021 Liu, Lian, Zhang, Zhu, Zhang, Wang, Wang, Liu, Ren, Zhang, Liu and Gao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Extra spindle pole bodies-like 1 expression in gliomas. (A) The expression of ESPL1 in a variety of malignant tumors. Red indicates that ESPL1 is higher than the corresponding normal control group, while green indicates that ESPL1 is highly expressed in the tumor. (B) ESPL1 expression in 50 gliomas and 4 normal brain tissues in GSE2223. The expression of ESPL1 in gliomas was significantly increased. (C) In the GSE4290 data, the expression of ESPL1 in 77 gliomas and 23 normal brain tissues was compared, and the expression of ESPL1 in gliomas increased. (D) Comparing 34 kinds of glioma tissue specimens with 13 normal brain tissue specimens in the GSE50161 data set, the expression level of ESPL1 in glioma tissue was significantly increased. (E) RT-qPCR experiments show that the expression level of ESPL1 in glioma cell lines (LN229, T98, and A172) is higher than that in human astrocytes. *p < 0.05 and ****p < 0.0001.