Table 3.
Percentage parasitemia and mean survival days of malaria-infected mice treated with the hydroalcoholic extract and solvent fractions of G. ternifolia stem barks in Rane's test.
| Groups | % parasitemia | % suppression | Survival time |
|---|---|---|---|
| DW | 53.09 ± 1.34 | 0.00 | 7.08 ± 0.27 |
| 200 mg/kg CE | 33.87 ± 1.52 | 36.22a∗∗∗b∗∗∗d∗∗∗e∗∗∗ | 9.00 ± 0.22b∗∗∗d∗e∗∗∗ |
| 400 mg/kg CE | 26.13 ± 1.65 | 50.79a∗∗∗b∗∗∗e∗∗ | 11.17 ± 0.38a∗∗∗b∗∗∗e∗∗ |
| 600 mg/kg CE | 20.33 ± 0.58 | 61.72a∗∗∗b∗∗∗ | 13.92 ± 0.92a∗∗∗b∗∗∗ |
| 25 mg/kg CQ | 0.00 ± 0.00 | 100.00a∗∗∗ | 28.00 ± 0.00a∗∗∗ |
Data are expressed as mean ± SEM (n = 6); a, compared with DW; b, compared with positive control; d, compared with 400 mg/kg; e, 600 mg/kg; ∗P < 0.05; ∗∗P < 0.01; ∗∗∗P < 0.001; DW for distilled water (negative control); CE for crude extract; CQ for chloroquine (positive control).