Table 4.
Multivariate logistic regression including rs2075650 SNP and TAS2R38 haplotypes
| Variable | OR | L95 | U95 | p |
|---|---|---|---|---|
| Haplotype: genotypic model | ||||
| rs2075650 = AG | 0.56 | 0.34 | 0.88 | 0.013 |
| rs2075650 = GG | 1.80 | 0.39 | 9.21 | 0.444 |
| Haplotype = AVI/AVI | 1.08 | 0.61 | 1.91 | 0.792 |
| Haplotype = PAV/AVI | 0.89 | 0.52 | 1.53 | 0.669 |
| Haplotype = PAV/PAV | 0.91 | 0.52 | 1.61 | 0.751 |
| Haplotype: additive model | ||||
| rs2075650 = AG | 0.56 | 0.35 | 0.88 | 0.015 |
| rs2075650 = GG | 1.73 | 0.38 | 8.85 | 0.473 |
| Haplotype = PAV | 0.88 | 0.54 | 1.44 | 0.595 |
| Haplotype = AVI | 0.94 | 0.58 | 1.54 | 0.796 |
Variable: variable included in the multivariate model (genotypic model: Haplotype = AVI/AVI: subjects carrying the AVI haplotype on both chromosomes, Haplotype = PAV/AVI: subjects carrying PAV on one chromosome and AVI on the other chromosome, Haplotype = PAV/PAV: subjects carrying the PAV haplotype on both chromosomes, carriers of the rare haplotype have been used as baseline value; Additive model: Haplotype = PAV: number of PAV haplotypes by subject, Haplotype = AVI: number of AVI haplotypes by subject); OR odds ratio for longevity, L95 lower bound of the OR 95% confidence interval; U95% upper bound of the OR 95% confidence interval