Table 3:
Percent accuracy, precision (relative standard deviation) and paired two tailed t-test (p-value) for noninvasive volume measures for suprachoroidal, subretinal, and intravitreal implants. P > 0.05 indicates no significant differences between the two types of measurements. Data are presented as mean SD for n=4–5 eyes. Key: SC- Suprachoroidal, SR- Subretinal, and IVT- Intravitreal, NE-Not estimated.
| Accuracy (%), precision (%) and p-value for volume estimation compared to blade micrometer values | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Accuracy (%) | Precision (%) | p-value | ||||||||
| SC | SR | IVT | SC | SR | IVT | SC | SR | IVT | ||
| Metal implant | ||||||||||
| 0.65×6.35 mm | cSLO image | 90±26 | 46±10 | 61±7 | 29 | 22 | 12 | 0.490 | 0.002 | 0.002 |
| OCT image-Integrated bleb area over length | 157±2 | 186±20 | NE | 2 | 11 | NE | 0.000 | 0.003 | ||
| cSLO image and thickness map | 79±7 | 105±23 | NE | 9 | 22 | NE | 0.009 | 0.680 | ||
| 0.57×6.35 mm | cSLO image | 93±25 | 70±18 | 65±11 | 26 | 25 | 17 | 0.624 | 0.043 | 0.008 |
| OCT image-Integrated bleb area over length | 154±69 | 200±44 | NE | 45 | 22 | NE | 0.217 | 0.020 | ||
| cSLO image and thickness map | 63±30 | 101±28 | NE | 47 | 27 | NE | 0.089 | 0.937 | ||
| 0.23×9.51 mm | cSLO image | 152±57 | 116±8 | 105±48 | 38 | 7 | 46 | 0.165 | 0.027 | 0.847 |
| OCT image-Integrated bleb area over length | 552±313 | 556±127 | NE | 57 | 23 | NE | 0.065 | 0.005 | ||
| cSLO image and thickness map | 111±56 | 279±53 | NE | 51 | 19 | NE | 0.731 | 0.007 | ||
| 1.27×6.45 mm | cSLO image | 65±29 | 62±6 | 102±14 | 45 | 10 | 14 | 0.097 | 0.001 | 0.800 |
| OCT image-Integrated bleb area over length | 124±48 | 252±37 | NE | 57 | 23 | NE | 0.394 | 0.004 | ||
| cSLO image and thickness map | 61±34 | 104±8 | NE | 51 | 19 | NE | 0.108 | 0.381 | ||
| Polymeric implant | ||||||||||
| ~0.4×2 mm | cSLO image | 42±31 | 95±33 | 94±14 | 89 | 41 | 18 | 0.045 | 0.790 | 0.509 |
| OCT image-Integrated bleb area over length | 117±54 | 165±79 | NE | 55 | 46 | NE | 0.660 | 0.125 | ||
| cSLO image and thickness map | 32±17 | 66±26 | NE | 61 | 38 | NE | 0.014 | 0.042 | ||
| ~0.4×4 mm | cSLO image | 55±32 | 104±17 | 81±7 | 55 | 16 | 11 | 0.080 | 0.789 | 0.003 |
| OCT image-Integrated bleb area over length | 135±11 | 175±33 | NE | 10 | 38 | NE | 0.007 | 0.044 | ||
| cSLO image and thickness map | 45±10 | 91±26 | NE | 27 | 45 | NE | 0.001 | 0.676 | ||
| ~0.4×6 mm | cSLO image | 104±42 | 85±15 | 67±6 | 28 | 30 | 8 | 0.977 | 0.111 | 0.002 |
| OCT image-Integrated bleb area over length | 183±58 | 181±30 | NE | 23 | 27 | NE | 0.044 | 0.014 | ||
| cSLO image and thickness map | 53±8 | 89±19 | NE | 21 | 35 | NE | 0.003 | 0.280 | ||