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. Author manuscript; available in PMC: 2022 Sep 5.
Published in final edited form as: Int J Pharm. 2021 Jul 14;606:120887. doi: 10.1016/j.ijpharm.2021.120887

Table 4:

Coefficient of determination (r2) and slope of a regression line of intraocular implant measurements obtained using different imaging approaches compared to those obtained using blade micrometer before the injection. Coefficient of determination and slope was not estimated for intravitreal metal and polymeric implants due to the absence of volume in thickness map and bleb in OCT image. Coefficient of determination and slope was not estimated for polymeric implant diameter due to the use of implants with a single diameter. Key: SC- Suprachoroidal, SR- Subretinal, and IVT- Intravitreal. NE- Not estimated.

Coefficient of determination (r2) when compared to blade micrometer values Slope of a regression line when compared to blade micrometer values
SC SR IVT SC SR IVT
Metal Implants
cSLO image-Length 0.837 0.974 0.880 0.647 0.997 1.005
cSLO image-Diameter 0.816 0.960 0.960 0.674 0.730 0.975
cSLO image-Volume 0.730 0.966 0.964 0.593 0.611 1.066
OCT image-Integrated bleb area over length-Volume 0.746 0.953 NE 1.076 2.507 NE
cSLO image and thickness map- Volume 0.670 0.974 NE 0.587 0.991 NE
Polymeric implants
cSLO image-Length 0.950 0.942 0.988 1.048 0.948 1.008
cSLO image-Diameter NE NE NE NE NE NE
cSLO image-Volume 0.551 0.852 0.862 1.079 0.818 0.541
OCT image-Integrated bleb area over length-Volume 0.733 0.903 NE 1.915 1.895 NE
cSLO image and thickness map- Volume 0.893 0.830 NE 0.641 0.642 NE