FIG. 1.

Bioluminescence of M. paratuberculosis K-10(pYUB180) after incubation for 3 (circles), 7 (squares), and 14 (triangles) days in broth cultures containing different antimicrobial agents (A and B). Bioluminescence (RLU × 0.001; y axis) is plotted against the drug concentration (in micrograms per milliliter; x axis). The value for each time point is the mean of three independent experiments. Bars representing standard deviations are indicated. The mean bioluminescence of the cultures immediately after inoculation (day 0) was 340 ± 170.