TABLE 2.

Comparison of broth macrodilution and bioluminescence MICs^a

Drug	Drug concn range (μg/ml)	Broth macro-dilution MIC (μg/ml)	Luciferase assay MIC (μg/ml)
			Day 7	Day 14
d-Cycloserine	0.8–100	25	25	25
Ethambutol	1.25–160	20	20	10
Isoniazid	1.95–250	≥250	≥250	≥250
Bay y 3118	0.008–1.0	0.015	0.015	0.008
Amikacin	0.5–64	2	16	2
Kanamycin	1–128	≥128	≥128	≥128
Clarithromycin	0.625–80	1.25	1.25	1.25
Rifabutin	0.03–4	0.5	0.5	0.5

^aMICs were determined as described in Materials and Methods.