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. Author manuscript; available in PMC: 2022 Oct 1.
Published in final edited form as: J Pathol. 2021 Jul 22;255(2):141–154. doi: 10.1002/path.5751

Figure 6. Immune subtypes and interactions with fibroblasts in BPH.

Figure 6.

(A) Subsetted leukocytes from normal human prostate samples (n=3 prostate donors) and BPH samples (n=6 BPH patients) with major immune lineages identified. (B) Immune composition of glandular (n=6) and stromal samples (n=6) from six BPH patients. (C) Dot plot of predicted interactions from fibroblasts to immune cells. (D) Immune subtypes in the prostate identified using Travaglini et al [21]. (E) Illustration depicting signals from fibroblasts to immune cells. Up arrows indicate genes upregulated in the fibroblast subtype in BPH. See also supplementary material, Figures S6, S7.