Table 3:
The risk of atopic dermatitis for KIR gene and reported HLA Class I epitope (as a composite) with respect to atopic dermatitis by ancestry presented with odds ratio and 95% confidence interval.
| Composite | Full Cohort | European Ancestry | African Ancestry | |
|---|---|---|---|---|
| KIR | HLA ligand | OR (95% CI) | OR (95% CI) | OR (95% CI) |
| 2DS2 | C1 | 0.88 (0.66,1.18) | 0.79 (0.54,1.15) | 1.42 (0.84,2.40) |
| 2DL2 | C1 | 0.90 (0.67,1.20) | 0.76 (0.52,1.10) | 1.53 (0.91,2.57) |
| 2DL3 | C1 | 0.97 (0.71,1.32) | 1.17 (0.77,1.78) | 0.91 (0.55,1.50) |
| 2DL1 | C2 | 0.95 (0.71,1.27) | 0.99 (0.68,1.44) | 1.27 (0.77,2.09) |
| 3DL1 | Bw4 | 0.96 (0.72,1.28) | 0.86 (0.59,1.25) | 1.31 (0.80,2.17) |
| 3DS1 | Bw4 | 1.14 (0.79,1.63) | 1.25 (0.81,1.93) | 1.39 (0.63,3.05) |
| 2DS1 | C2 | 1.48 (1.04,2.12) p=0.003 |
1.48 (0.96,2.28) | 2.68 (1.23,5.82) p=0.01 |
| 2DS5 | C2 | 1.74 (1.21,2.51) p=0.003 |
1.68 (1.06,2.68) p=0.02 |
2.23 (1.17,4.25) p=0.01 |