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. Author manuscript; available in PMC: 2022 Oct 1.
Published in final edited form as: Bioorg Med Chem Lett. 2021 Jul 21;49:128272. doi: 10.1016/j.bmcl.2021.128272

Figure 1.

Figure 1.

Known properties of dimeric chloroquines and dimeric quinacrines. A. Generic structure of dimeric chloroquines B. Effect of linker carbon length on inhibitory potencies C. Generic structure of dimeric quinacrines and effect of central nitrogen methylation on autophagy and DNA damage with dimeric quinacrines. (For both 1B and 1C, m, n, and R are defined in the text).