Table 4.

The proportion (%, SE) with cognitive impairment in the total population by A1c level among adults age ≥60 years, NHANES 2011–2014

	A1c< 7.0% (<53 mmol/mol)	A1c 7.0– <8.0% (53– <64 mmol/mol)	A1c ≥8.0% (≥64 mmol/mol)
CERAD WL Delayed
Model 1	4.5 (0.70)	3.5 (1.56)	9.7 (3.73)
Model 2	4.5 (0.70)	3.5 (1.55)	9.6 (3.81)
Model 3	4.5 (0.70)	2.5 (1.54)	9.8 (3.98)
Model 4	4.0 (0.70)	2.3 (1.62)	8.9 (3.72)
Model 5	3.9 (0.69)	3.2 (1.67)	9.6 (3.71)
Model 6	4.0 (0.73)	2.0 (1.32)	9.4 (3.70)
Model 7	4.0 (0.72)	2.1 (1.38)	9.3 (3.67)
CERAD WL Total
Model 1	5.4 (0.85)	3.0 (1.56)	11.4 (4.59)
Model 2	5.4 (0.85)	2.9 (1.57)	11.2 (4.56)
Model 3	5.5 (0.86)	1.9 (1.59)	11.5 (4.77)
Model 4	5.2 (0.86)	1.5 (1.70)	10.4 (4.52)
Model 5	5.1 (0.87)	2.4 (1.91)	11.1 (4.38)
Model 6	5.1 (0.91)	1.3 (1.43)	11.0 (4.58)
Model 7	5.1 (0.91)	1.2 (1.49)	11.1 (4.61)
Animal Fluency
Model 1	5.5 (1.02)	6.5 (2.35)	6.6 (2.75)
Model 2	5.5 (1.01)	6.5 (2.34)	6.6 (2.84)
Model 3	5.1 (1.01)	4.8 (2.28)	6.9 (2.93)
Model 4	4.7 (0.94)	3.8 (2.83)	6.6 (2.94)
Model 5	4.4 (0.84)	3.5 (2.68)	7.0 (3.13)
Model 6	4.6 (0.87)	3.2 (2.94)	6.7 (3.11)
Model 7	4.6 (0.87)	2.7 (2.78)	7.2 (3.09)
DSST
Model 1	7.4 (1.16)	5.7 (1.36)	14.8 (4.20)
Model 2	7.4 (1.16)	5.7 (1.35)	14.9 (4.18)
Model 3	7.0 (1.09)	4.0 (1.63)	14.5 (3.97)
Model 4	6.5 (1.02)	3.4 (1.85)	14.5 (4.14) *
Model 5	6.2 (0.94)	3.2 (2.10)	14.9 (4.10) *
Model 6	6.3 (0.97)	2.3 (1.82)	14.7 (4.17) *
Model 7	6.3 (0.98)	2.3 (1.72)	14.6 (4.26) *

^*p<0.05 vs. A1c <7.0%

Cognitive impairment defined as ≤1.5 SD of the mean cognitive test score for the NHANES population

Model 1: Adjusted for age, race/ethnicity

Model 2: Model 1 + sex

Model 3: Model 2 + education, income

Model 4: Model 3 + smoking status, alcohol consumption, exercise

Model 5: Model 4 + body mass index

Model 6: Model 5 + hypertension, hyperlipidemia, history of CVD

Model 7: Model 6 + depression, history of stroke