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. 2021 Mar 8;60(16):2693–2696. doi: 10.2169/internalmedicine.6975-20

Table.

Review of Previous Case Reports on Headache with Thyrotoxicosis.

Reference number Age Sex PHx of migraine FHx of migraine Nausea/
Vommiting
Heart rate Papilledema Tremor Tendon
reflex
BW loss fT3 fT4 TSH TRAb TPOAb Diagnosis Treatment Improvement
4 N/A F + N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A Graves’ disease N/A N/A
N/A F + N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
N/A F + N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
N/A F + N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A Overtreatment of hypothyroidism N/A N/A
5 32 F - - + 114 bpm + + - >20 9.4 <0.03 + - Graves’ disease propranolol 120 mg, carbimazole 45 mg +
6 34 F +(MO) - + 120 bpm N/A + N/A N/A 10.3 <0.05 + N/A Graves’ disease propranolol 40 mg, carbimazole 60 mg +
51 F - - + N/A - + N/A N/A 10.4 <0.05 + N/A Graves’ disease carbimazole +
20 F - - + 120 bpm - + + N/A 4.7 <0.05 + N/A Graves’ disease carbimazole→surgery +(after surgery)
8 58 F - N/A + 134 bpm N/A N/A N/A + N/A 5.3 <0.05 N/A N/A Small multinodular goitre carbimazole, propranolol +
9 58 M N/A N/A + 116 bpm + N/A N/A 7.7 4.6 0.07 N/A - Thyroid nodule propylthiouracil 300 mg, propranolol 40 mg, dexamethasone 24 mg +
10 15 M - - N/A 105 bpm N/A N/A N/A N/A >33 >7.8 0.02 N/A N/A N/A methimazole +
Current Case 18 M +(MA) + + 70 bpm - - + 8.5 3.6 0.01 - - Painless thyroditis atenolol 25mg +

Units for fT3, fT4, and TSH are pg/mL, ng/dL, and μIU/mL, respectively. N/A: not available, F: female, M: male, PHx: past history, MA: migraine with aura, MO: migraine without aura, FHx: family history, bpm: beats per minute, BW: body weight, ↑: hyperreflexia, →: normal, ↓: hyporeflexia