Table 2.
Interactions between age and CR for different cognitive domains
| Cognitive domain | Episodic memory | Working memory | Fluency | Flexibility | Planning | Inhibition | Information processing speed |
|---|---|---|---|---|---|---|---|
| Age | − 0.06 (− 0.09– − 0.02)****† | − 0.01 (− 0.04–0.02) | − 0.02 (− 0.05–0.02) | − 0.04 (− 0.07–0.00)* | − 0.05 (− 0.15–0.04) | − 0.31 (− 0.69–0.07) | − 0.04 (− 0.08– − 0.01)** |
| CR | 0.09 (− 0.10–0.28) | 0.32 (0.13–0.50)****† | 0.55 (0.36–0.74)****† | 0.15 (− 0.07–0.38) | 0.14 (− 0.42–0.70) | 0.38 (-1.87–2.63) | 0.32 (0.12–0.52)***† |
| Sex | 0.36 (0.01–0.71)** | 0.12 (− 0.21–0.46) | 0.15 (− 0.20–0.50) | 0.41 (0.00–0.83)* | 0.05 (− 0.98–1.08) | 1.55 (− 2.62–5.71) | 0.10 (− 0.27–0.47) |
| Age*CR | 0.02 (− 0.02–0.05) | 0.02 (-0.01–0.06) | 0.05 (0.02–0.09)***† | 0.04 (0.00–0.08)* | 0.02 (− 0.08–0.12) | 0.16 (− 0.25–0.56) | 0.01 (− 0.03–0.05) |
| Finteraction | F(1,76) = 1.06 | F(1,78) = 1.93 | F(1,78) = 8.86 | F(1,75) = 3.55 | F(1,63) = 0.14 | F(1,73) = 0.58 | F(1,76) = 0.24 |
| ∆R2interaction | 0.01 | 0.02 | 0.08 | 0.04 | 0.00 | 0.01 | 0.00 |
| R2total | 0.22 | 0.15 | 0.32 | 0.16 | 0.02 | 0.06 | 0.19 |
| Cohen’s f2total | 0.28 | 0.17 | 0.47 | 0.19 | 0.03 | 0.06 | 0.23 |
B values are reported, together with lower and upper borders of the 95% confidence interval. Higher cognitive domain scores indicate better performance. Cohen’s f2 calculations are based on the unrounded R2 values
CR cognitive reserve (compound score of educational attainment and verbal intelligence estimate)
*Uncorrected p < 0.07
**Uncorrected p < 0.05
***Uncorrected p < 0.01
****Uncorrected p < 0.001
†Survived FDR corrections