Table 1.
Demographic and clinical characteristics of the study population at baseline
| Calcifediol (20 µg/die) (N = 23) | Calcifediol (30 µg/die) (N = 23) | |
|---|---|---|
| Age (years) | 62.4 ± 7.4 | 61.5 ± 8.3 |
| BMI (kg/m2) | 26.1 ± 3.2 | 25.5 ± 4.0 |
| Age of Menopause (years) | 50.5 ± 3.3 | 49.7 ± 4.6 |
| Calcium (mg/dl) | 9.3 ± 0.3 | 9.4 ± 0.4 |
| Phosphate (mg/dl) | 3.5 ± 0.3 | 3.7 ± 0.4 |
| Creatinine (mg/dl) | 0.7 ± 0.1 | 0.7 ± 0.2 |
| Urinary calcium (mg/24 h) | 158.1 ± 70.4 | 149.5 ± 69.1 |
| ALP (UI/L) | 76.8 ± 13.4 | 76.9 ± 23.6 |
| 25OHD (ng/ml) | 15.2 ± 4.7 | 16.2 ± 5.1 |
| 1,25(OH)D2 (pg/ml) | 44.9 ± 11.8 | 45.5 ± 11.3 |
| PTH (pg/ml) | 42.6 ± 15.1 | 43.8 ± 14.4 |
| B-ALP (µg/l) | 15.1 ± 5.6 | 13.5 ± 4.3 |
| β-CTX (ng/l) | 459 ± 207 | 490 ± 120 |
| LS-BMD (g/cm2) | 0.967 ± 0.159 | 0.957 ± 0.107 |
| LS T-score | − 1.47 ± 1.17 | − 1.52 ± 0.79 |
| TH-BMD (g/cm2) | 0.835 ± 0.135 | 0.822 ± 0.084 |
| TH T-score | − 1.18 ± 1.20 | − 1.26 ± 0.75 |
| FN-BMD (g/cm2) | 0.744 ± 0.129 | 0.762 ± 0.112 |
| FN T-score | − 1.76 ± 1.03 | − 1.57 ± 0.66 |
| Fat mass (kg) | 28.9 ± 7.8 | 28.8 ± 6.9 |
| Lean mass (kg) | 37.9 ± 5.4 | 37.1 ± 5.2 |
| Calcium Intake (mg/day) | 684.0 ± 279.3 | 709.9 ± 322.1 |
| Myostatin (ng/ml) | 10.18 ± 5.91 | 11.07 ± 5.69 |
| Right handgrip (kg) | 18.47 ± 4.66 | 18.29 ± 4.86 |