Table 2.

Univariate and multivariate Cox regression analysis of overall survival in patients with gastric cancer.

Variables	Univariate cox analysis		Multivariate cox analysis
	HR (95% CI)	P value	HR (95% CI)	P value
Gender (male vs. female)	1.45(0.95–2.20)	0.082	1.56 (1.02–2.39)	0.042*
Age (≥65 vs. <65)	1.86(1.33–2.61)	<0.001*	1.84 (1.31–2.58)	<0.001*
T (T3 + T4 vs. Tis + T1 + T2)	3.87(2.39–6.27)	<0.001*	1.78 (0.95–3.34)	0.072
N (N2 + N3 vs. N0 + N1)	2.28(1.64–3.16)	<0.001*	1.13 (0.74–1.74)	0.557
Stage (III + IV vs. I + II)	3.15(2.19–4.55)	<0.001*	1.86(1.16–2.97)	0.01*
Differentiation (Poor vs. Moderate + Well)	2.10(1.40–3.13)	<0.001*	1.71(1.13–2.69)	0.01*
Tumor size (>4.75 cm vs. ≤4.75 cm)	2.20 (1.59–3.05)	<0.001*	1.67(1.19–2.34)	0.03*
NSUN2 expression (high vs. low)	1.69(1.02–2.81)	0.042*	1.55(0.93–2.59)	0.09

^*Statistically significant (P < 0.05).