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. 2021 Sep 9;7:79. doi: 10.1038/s41531-021-00221-7

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© The Author(s) 2021

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Fig. 3 — a Chromosome 17 regional association plot (part 1). b Chromosome 17 regional association plot (part 2). c Chromosome 16 regional association plot. d Chromosome 7 regional association plot. The marginally associated TWAS genes are shown in blue, and the conditionally significant genes are shown in green. The bottom panel shows a regional Manhattan plot of the GWAS data before (gray) and after (blue) conditioning on the green genes’ predicted expression.