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. 2021 Sep 9;11:17973. doi: 10.1038/s41598-021-97465-3

Table 1.

Predictive variables routinely collected at first antenatal visit in the study population of 58 899 nulliparous women.

Predictive variables collected at first antenatal visit N Without preeclampsia n = 56,323 With preeclampsia n = 2576 P-value
N N
Maternal age, years* 29.3 (5.0) 29.9 (5.3) < 0.001
Region of birth n, % < 0.001
Sweden 41,778 75.2 2021 80.1
Nordic countries (except of Sweden) 896 1.6 39 1.5
Europe (except of Nordic countries) 4235 7.6 144 5.7
Africa 1759 3.2 101 4.0
North America 368 0.7 13 0.5
South America 951 1.7 33 1.3
Asia 5544 10.0 170 6.7
Oceania 50 0.1 3 0.1
Missing n 794
Family situation n, % 0.16
Single 1159 2.1 67 2.6
Living with partner 51,781 92.5 2354 92.1
Other 3028 5.4 136 5.3
Missing n 374
Height, cm* 166.6 6.5 166.1 6.5 < 0.001
Missing n 395
Smoking 3 months before pregnancy n, % 0.38
< 10 4881 8.7 220 8.6
≥ 10 4093 7.3 169 6.6
Missing n 365
Smoking at registration n, % 0.082
< 10 1952 3.5 70 2.7
≥ 10 353 0.6 20 0.8
Missing n 333
Previous miscarriage n, % 9924 17.6 486 18.9 0.10
Infertility duration, years, % < 0.001
1–2 6223 11.0 300 11.6
> 2 3016 5.4 201 7.8
Infertility treatment n, % 0.009
Ovarian stimulation 816 1.4 44 1.7
IVF 3717 6.6 207 8.0
Family history of preeclampsia n, % 140 0.2 16 0.6 < 0.001
Family history of hypertension n, % 9358 16.6 593 23.0 < 0.001
Cardiovascular disease n, % 732 1.3 46 1.8 0.035
Endocrine disease n, % 2770 4.9 164 6.4 < 0.001
Pre-existing diabetes n, % 247 0.4 59 2.3 < 0.001
Thrombosis history n, %
SLE n, % 61 0.1 3 0.1 0.90
Chronic hypertension n, % 247 0.4 40 1.6 < 0.001
Mb Crohn/Ulcerative colitis n, % 478 0.8 17 0.7 0.30
Chronic kidney disease n, % 249 0.4 26 1.0 < 0.001
Blood group n, % 0.15
0 19,828 38.1 869 36.8
A 22,385 43.1 1034 43.8
AB 2881 5.5 117 5.0
B 6897 13.3 342 14.5
Missing n 4546

*Mean (SD).