Table 1.
Predictive variables routinely collected at first antenatal visit in the study population of 58 899 nulliparous women.
Predictive variables collected at first antenatal visit | N | Without preeclampsia n = 56,323 | With preeclampsia n = 2576 | P-value | ||
---|---|---|---|---|---|---|
N | N | |||||
Maternal age, years* | 29.3 (5.0) | 29.9 (5.3) | < 0.001 | |||
Region of birth n, % | < 0.001 | |||||
Sweden | 41,778 | 75.2 | 2021 | 80.1 | ||
Nordic countries (except of Sweden) | 896 | 1.6 | 39 | 1.5 | ||
Europe (except of Nordic countries) | 4235 | 7.6 | 144 | 5.7 | ||
Africa | 1759 | 3.2 | 101 | 4.0 | ||
North America | 368 | 0.7 | 13 | 0.5 | ||
South America | 951 | 1.7 | 33 | 1.3 | ||
Asia | 5544 | 10.0 | 170 | 6.7 | ||
Oceania | 50 | 0.1 | 3 | 0.1 | ||
Missing n | 794 | |||||
Family situation n, % | 0.16 | |||||
Single | 1159 | 2.1 | 67 | 2.6 | ||
Living with partner | 51,781 | 92.5 | 2354 | 92.1 | ||
Other | 3028 | 5.4 | 136 | 5.3 | ||
Missing n | 374 | |||||
Height, cm* | 166.6 | 6.5 | 166.1 | 6.5 | < 0.001 | |
Missing n | 395 | |||||
Smoking 3 months before pregnancy n, % | 0.38 | |||||
< 10 | 4881 | 8.7 | 220 | 8.6 | ||
≥ 10 | 4093 | 7.3 | 169 | 6.6 | ||
Missing n | 365 | |||||
Smoking at registration n, % | 0.082 | |||||
< 10 | 1952 | 3.5 | 70 | 2.7 | ||
≥ 10 | 353 | 0.6 | 20 | 0.8 | ||
Missing n | 333 | |||||
Previous miscarriage n, % | 9924 | 17.6 | 486 | 18.9 | 0.10 | |
Infertility duration, years, % | < 0.001 | |||||
1–2 | 6223 | 11.0 | 300 | 11.6 | ||
> 2 | 3016 | 5.4 | 201 | 7.8 | ||
Infertility treatment n, % | 0.009 | |||||
Ovarian stimulation | 816 | 1.4 | 44 | 1.7 | ||
IVF | 3717 | 6.6 | 207 | 8.0 | ||
Family history of preeclampsia n, % | 140 | 0.2 | 16 | 0.6 | < 0.001 | |
Family history of hypertension n, % | 9358 | 16.6 | 593 | 23.0 | < 0.001 | |
Cardiovascular disease n, % | 732 | 1.3 | 46 | 1.8 | 0.035 | |
Endocrine disease n, % | 2770 | 4.9 | 164 | 6.4 | < 0.001 | |
Pre-existing diabetes n, % | 247 | 0.4 | 59 | 2.3 | < 0.001 | |
Thrombosis history n, % | ||||||
SLE n, % | 61 | 0.1 | 3 | 0.1 | 0.90 | |
Chronic hypertension n, % | 247 | 0.4 | 40 | 1.6 | < 0.001 | |
Mb Crohn/Ulcerative colitis n, % | 478 | 0.8 | 17 | 0.7 | 0.30 | |
Chronic kidney disease n, % | 249 | 0.4 | 26 | 1.0 | < 0.001 | |
Blood group n, % | 0.15 | |||||
0 | 19,828 | 38.1 | 869 | 36.8 | ||
A | 22,385 | 43.1 | 1034 | 43.8 | ||
AB | 2881 | 5.5 | 117 | 5.0 | ||
B | 6897 | 13.3 | 342 | 14.5 | ||
Missing n | 4546 |
*Mean (SD).