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. 2021 Sep 9;11:17919. doi: 10.1038/s41598-021-97482-2

Table 1.

Maternal findings of the studied pregnancies.

Controls N° 34 IUGR N° 34 p-value§ e-PE N° 29 p-value§§ p-value$ l-PE N° 7 p-value§§§ p-value£
Maternal age (years) 32.7 ± 4.9 33.4 ± 5.7 0.568 36.2 ± 5.1 0.008 0.048 34.0 ± 4.2 0.508 0.059
Body Mass Index (BMI) (kg/m2) 23.8 ± 3.2 25.9 ± 4.2 0.031 23.3 ± 3.5 0.540 0.012 30.9 ± 3.7  < 0.0001  < 0.0001
Ethnicity Caucasian 100% Caucasian 100% Caucasian 100% Caucasian 100%
Highest systolic blood pressure (mmHg) 108.7 ± 15.9 118.8 ± 16.6 0.012 147.8 ± 20.0  < 0.0001  < 0.0001 151.4 ± 10.7  < 0.0001  < 0.0001
Highest diastolic blood pressure (mmHg) 69.3 ± 8.7 67.9 ± 13.2 0.604 94.6 ± 12.4  < 0.0001  < 0.0001 100.7 ± 10.2  < 0.0001  < 0.0001
Maximum proteinuria value (g/L) 0.1 ± 0.2 0.1 ± 0.2 0.173 4.2 ± 3.4  < 0.0001  < 0.0001 1.7 ± 0.7  < 0.0001  < 0.0001
Gravidity 1.8 ± 1.1 1.9 ± 1.2 0.668 1.8 ± 1.5 0.866 0.603 1.4 ± 0.8 0.343 0.755
Parity 0.3 ± 0.7 0.5 ± 0.8 0.214 0.3 ± 0.7 0.967 0.255 0.0 ± 0.0 0.253 0.256

§Two-independent sample t-test (IUGR vs. Controls).

§§Two-independent sample t-test (e-PE vs. Controls).

$Two-independent sample t-test (IUGR vs. e-PE).

§§§Two-independent sample t-test (l-PE vs. Controls).

£Anova Test among the four groups (Controls vs. IUGR vs. e-PE vs. l-PE).

IUGR Intrauterine Growth Restriction; PE Preeclampsia; e-PE Early-onset PE; l-PE Late-onset PE.