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. 2021 Jun 24;46(11):1918–1926. doi: 10.1038/s41386-021-01071-w

Fig. 4. Intra-aINS prazosin reduced both AOD and CLAD.

Fig. 4

Prazosin (0.3 µg/side) in aINS reduced AOD and CLAD drinking (A) but not saccharin intake (B). (C) A lower dose of prazosin (0.1 µg/side) in aINS had no effect on AOD or CLAD drinking compared with vehicle (F(treatment;1,10) = 0.319, p = 0.585; F(drinking-condition;1,10) = 5.865, p = 0.036; F(interaction;1,10) = 0.588, p = 0.461), although there was small (~21.5%) but significant lower CLAD vs. AOD intake. (D) For 0.3-µg/side aINS prazosin, changes in AOD were not correlated with changes in CLAD. **,***: p < 0.01, p < 0.005.