Table 2.

Procedural and monitoring protocols of the included studies.

Study	Arrhythmia monitoring methodology	Protocol of AADs after ablation	Cryoablation protocol	Radiofrequency ablation protocol
Andrade	Implantable Loop Recorder	Discontinued after the blanking period	Cryoablation was performed with a lesion duration of 4 min or 2 min	The CF targeted prior to lesion delivery was 20 g (10–40 g), with a minimum individual FTI > 400 gs
You	NR	NR	Cryoablation was performed up to 180 s and two times for each PV	Standardized RFCA procedure
Giannopoulos	NR	Discontinued after the blanking period	Cryoablation energy was applied for 240 s; if no PV signals were recorded in a vein the time of energy delivery was reduced to 180 s	Standardized RFCA procedure
Buist	ECG; 24–72 h Holter ECG	Discontinued after the blanking period	Cryo-energy applications were performed up to 240 s, with an additional number of cryo applications at the operator’s discretion	Power setting was adjusted between 30–40 w, RF application duration of 20 to 40 s, FTI > 400 gs
Watanabe	ECG; Holter ECG	Discontinued after the blanking period	A 180 s-freeze was delivered to each PV	RF energy was delivered with a maximum power of 30 W, CF of 10–15 g
Gunawardene	ECG ; 5-day Holter ECG	Discontinued after the ablation	Target application time was 240 s (332.0 + 159.3 s per PV and 1.54 + 0.76 cryo freezes per PV, as results)	RF energy was delivered with a maximum power of 30 W for 30–60 s, temperature limit of 45℃, minimal CF of 10 g

AADs = antiarrhythmic drugs, ECG = electrocardiograph, PV = pulmonary vein, CF = contact force, FTI = force–time integral, RFCA = radiofrequency catheter ablation, NR = not reported.