Table 4.
Comparison of the diagnostic efficacy of the DNA microarray method when sputum smear grades were ≤ 1 + and ≥ 2 +
| CapitalBio DNA microarray | Sensitivity (%) | Specificity (%) | AR (%) | PPV (%) | NPV (%) | k |
|---|---|---|---|---|---|---|
| RIF | ||||||
| ≤ AFB 1 + | 72.6 | 97.7 | 96.5 | 62.4 | 98.6 | 0.65 |
| ≥ AFB 2 + | 84.5 | 97.5 | 96.5 | 74.5 | 98.7 | 0.77 |
| INH | ||||||
| ≤ AFB 1 + | 67.3 | 97.0 | 93.7 | 73.9 | 95.9 | 0.67 |
| ≥ AFB 2 + | 78.2 | 97.1 | 95.2 | 75.6 | 97.5 | 0.74 |
| MDR-TB | ||||||
| ≤ AFB 1 + | 60.0 | 99.0 | 97.5 | 72.0 | 98.4 | 0.64 |
| ≥ AFB 2 + | 73.9 | 99.0 | 97.7 | 80.8 | 98.5 | 0.76 |
DST drug sensitivity test, R resistant, S susceptible, AR agreement rate, PPV positive predictive value, NPV negative predictive value, AFB acid-fast bacilli.