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. 2021 Sep 9;11:18006. doi: 10.1038/s41598-021-97587-8

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Box plots of intact parathyroid hormone (iPTH) concentrations before and after 12 weeks of cinacalcet treatment of 135 participants (a) Baseline iPTH data (b) iPTH concentration after 12 weeks of cinacalcet treatment (c) Absolute change of iPTH concentration from baseline to 12 weeks (d) Percentage change of iPTH concentration from baseline to 12 weeks. In each box, the top, the middle line, and the bottom represent the 75th percentile, the median, and the 25th percentile, respectively. The whiskers show the maximum and the minimum. The data were compared by Kruskal–Wallis test among three genotypes and by Mann–Whitney test between two genotypes. *p < 0.05 was considered statistically significant.