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. 2021 Sep 9;11:18007. doi: 10.1038/s41598-021-97390-5

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Cell proliferation with CXCL10 treatment. CXCL10 promoted cell proliferation in MCF-7 after 24 h and 48 h with a significantly increased percentage of cell proliferation in all doses added, of 20 ng/ml, 40 ng/ml, 60 ng/ml, 80 ng/ml, and 100 ng/ml, respectively (all p < 0.05). In MDA-MB-231, 40 ng/ml, 60 ng/ml, 80 ng/ml, and 100 ng/ml of CXCL10 significantly increased the percentage of cell proliferation after 24 h (p < 0.05) and 60 ng/ml, 80 ng/ml, and 100 ng/ml significantly increased cell proliferation after 48 h (p < 0.05). *Statistically significant. The graphs were created using GraphPad Prism version 8.02 for Windows (GraphPad Sofware, San Diego, CA, USA, www.graphpad.com).