Table 1.
List of top 20 genes with a significant fold change between DCIS and invasive carcinoma.
| Gene (mRNA) | Log2 fold change | p value | Adjusted p value* |
|---|---|---|---|
| CXCL10 | 2.92 | 6.50E−07 | 0.003 |
| LAG3 | 2.39 | 9.43E−05 | 0.114 |
| IL32 | 2.35 | 0.00039 | 0.206 |
| CXCL9 | 2.26 | 7.67E−06 | 0.019 |
| PDCD1LG2 | 1.93 | 0.00018 | 0.145 |
| CD96 | 1.82 | 0.00182 | 0.532 |
| SH2D1A | 1.81 | 0.00187 | 0.532 |
| CD5 | 1.68 | 0.00249 | 0.631 |
| TAP1 | 1.64 | 0.00128 | 0.476 |
| HLA-DRA | 1.55 | 0.00025 | 0.173 |
| CCL5 | 1.55 | 0.00043 | 0.206 |
| STAT1 | 1.41 | 0.00113 | 0.452 |
| PLAU | 1.37 | 1.18E−05 | 0.019 |
| HLA-DPA1 | 1.27 | 0.00070 | 0.305 |
| C1S | 1.24 | 0.00018 | 0.145 |
| CXCR4 | 0.95 | 0.00184 | 0.532 |
| BIRC5 | 0.95 | 0.00226 | 0.605 |
| CK1 | 0.90 | 0.00184 | 0.532 |
| VCAM1 | 0.78 | 0.00266 | 0.640 |
| CXCL2 | -1.21 | 0.00041 | 0.206 |
*p values were adjusted by Benjamini-Yekutieli procedure.