Table 2.
Summary of outcomes stratified by neurological conditions.
| Cerebral Palsy (n = 11) | Fibromyalgia, Chronic fatigue syndrome, CRPS (n = 15) | Muscular dystrophy, neuromuscular diseases (n = 22) | Multiple Sclerosis (n = 67) | Parkinson's disease (n = 36) | Spinal Cord Injury (n = 32) | Other (n = 16) | Overall (n = 199) | |
|---|---|---|---|---|---|---|---|---|
| HAQ SDI | ||||||||
| Median [Q1, Q3] | 1.63 [1.22, 1.75] | 1.38 [1.00, 1.88] | 2.00 [1.75, 2.25] | 1.43 [1.00, 1.94] | 0.57 [0.37, 1.14] | 1.69 [1.47, 2.16] | 1.81 [1.47, 2.00] | 1.50 [1.00, 2.00] |
| Pain | ||||||||
| Median [Q1, Q3] | 4.00 [2.50, 5.50] | 6.00 [3.50, 8.00] | 5.50 [3.25, 7.00] | 3.00 [1.00, 6.00] | 3.00 [1.00, 5.00] | 6.00 [2.75, 7.25] | 6.00 [2.00, 8.00] | 4.00 [2.00, 7.00] |
| Fear of COVID 19 SCORE | ||||||||
| Median [Q1, Q3] | 19.0 [15.0, 20.5] | 18.0 [12.0, 22.5] | 16.0 [14.3, 22.0] | 19.0 [14.5, 22.0] | 16.0 [11.8, 20.3] | 17.0 [10.8, 22.3] | 17.0 [14.0, 19.3] | 17.0 [13.0, 22.0] |
| UCLA loneliness SCORE | ||||||||
| Median [Q1, Q3] | 50.0 [39.0, 52.5] | 47.0 [38.5, 51.0] | 42.0 [30.8, 53.5] | 45.0 [35.0, 56.5] | 40.0 [33.5, 45.5] | 42.5 [27.8, 54.3] | 58.5 [49.3, 62.0] | 44.0 [33.5, 55.0] |
| SVS SCORE | ||||||||
| Median [Q1, Q3] | 3.00 [2.67, 3.42] | 2.17 [1.59, 2.83] | 2.67 [1.75, 3.63] | 3.17 [1.67, 4.17] | 3.33 [2.13, 3.87] | 3.34 [2.12, 4.17] | 1.83 [1.59, 2.54] | 3.00 [1.67, 4.00] |
| FSS SCORE | ||||||||
| Median [Q1, Q3] | 40.0 [30.5, 53.5] | 59.0 [56.0, 62.5] | 51.0 [35.5, 58.0] | 50.0 [39.5, 58.0] | 42.5 [31.8, 46.3] | 47.0 [26.8, 62.0] | 49.5 [41.8, 55.3] | 48.0 [37.0, 58.0] |
| Global fatigue | ||||||||
| Median [Q1, Q3] | 6.00 [4.00, 7.00] | 4.00 [1.50, 6.50] | 5.00 [3.00, 7.00] | 5.00 [3.00, 8.00] | 5.50 [4.00, 8.00] | 6.50 [3.00, 8.00] | 4.00 [2.00, 6.00] | 5.00 [3.00, 8.00] |
| Anxiety SCORE* | ||||||||
| Median [Q1, Q3] | 9.00 [6.00, 12.0] | 10.0 [6.50, 14.0] | 5.00 [4.00, 8.75] | 7.00 [5.00, 11.0] | 6.50 [5.00, 9.00] | 7.50 [2.00, 11.0] | 9.50 [7.25, 13.0] | 7.00 [5.00, 11.0] |
| Normal, n (%) | 4 (36.4%) | 5 (33.3%) | 13 (59.1%) | 37 (55.2%) | 23 (63.9%) | 16 (50.0%) | 4 (25.0%) | 102 (51.3%) |
| Borderline abnormal, n (%) | 3 (27.3%) | 3 (20.0%) | 6 (27.3%) | 12 (17.9%) | 7 (19.4%) | 6 (18.8%) | 5 (31.2%) | 42 (21.1%) |
| Abnormal, n (%) | 4 (36.4%) | 7 (46.7%) | 3 (13.6%) | 18 (26.9%) | 6 (16.7%) | 10 (31.2%) | 7 (43.8%) | 55 (27.6%) |
| Depression SCORE* | ||||||||
| Median [Q1, Q3] | 6.00 [4.00, 7.00] | 9.00 [6.00, 10.5] | 6.00 [5.00, 10.0] | 8.00 [5.00, 11.0] | 5.00 [3.00, 7.00] | 7.00 [2.75, 11.0] | 10.5 [6.50, 12.5] | 7.00 [4.00, 10.0] |
| Normal, n (%) | 10 (90.9%) | 6 (40.0%) | 13 (59.1%) | 33 (49.3%) | 29 (80.6%) | 17 (53.1%) | 5 (31.2%) | 113 (56.8%) |
| Borderline abnormal, n (%) | 1 (9.1%) | 5 (33.3%) | 4 (18.2%) | 16 (23.9%) | 5 (13.9%) | 6 (18.8%) | 3 (18.8%) | 40 (20.1%) |
| Abnormal, n (%) | 0 (0%) | 4 (26.7%) | 5 (22.7%) | 18 (26.9%) | 2 (5.6%) | 9 (28.1%) | 8 (50.0%) | 46 (23.1%) |
HAQ SDI, Health Assessment Questionnaire - Standard Disability Index; FSS, Fatigue Severity Scale; SVS, Subjective Vitality Scale, UCLA, University of California Los Angeles.
*
Scores across the respective 7 items for anxious and depressive symptoms from the Hospital Anxiety and Depression Scale (HADS) were summed together and the following scoring thresholds utilized to characterize participants: 0–7 = Normal, 8–10 = Borderline abnormal (borderline case), 11–21 = Abnormal (case).