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. 2021 Sep 9;11:18000. doi: 10.1038/s41598-021-97339-8

Figure 7.

Figure 7

Comparison of the competitive ELISA formats between aptamer–antibody (Apt/Ab) and antibody–antibody (Ab/Ab) sandwich systems. (a,b) Schematic representation of the components in each system, using four DEN-NS1 serotypes. In the Ab/Ab system, the same antibodies for the capture and detection reagents were used. In the Apt/Ab system, each UB-DNA aptamer was used for each DEN-NS1 serotype. (c) Comparison of ELISA signal patterns (inhibition) of each clinical sample in different time courses.