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. 2021 Sep 9;11:18017. doi: 10.1038/s41598-021-97520-z

Table 4.

Dosimetric evaluation of the IPSL and heart to left breast cancer patients between the SEB-HFWBI and SIB-HFWBI plans in the same position (mean).

Parameters SEB-HFWBI SIB-HFWBI T-value P-value
Ipsilateral lung supine
V5 (%) 31.52 ± 5.64 30.91 ± 5.65 4.479 0.000
V10 (%) 22.71 ± 5.46 22.45 ± 5.47 6.632 0.000
V20 (%) 18.20 ± 5.21 18.06 ± 5.22 5.771 0.000
V30 (%) 15.11 ± 4.99 14.89 ± 5.02 7.550 0.000
V40 (%) 6.16 ± 3.83 4.41 ± 3.28 9.766 0.000
Dmean (Gy) 9.24 ± 1.98 8.96 ± 1.93 9.251 0.000
Prone
V5 (%) 13.12 ± 6.95 12.76 ± 6.89 4.479 0.000
V10 (%) 8.70 ± 5.88 8.54 ± 5.83 6.632 0.000
V20 (%) 5.10 ± 3.95 4.89 ± 3.86 5.771 0.000
V30 (%) 3.15 ± 2.83 3.00 ± 2.76 7.550 0.000
V40 (%) 1.28 ± 1.55 0.79 ± 1.23 9.766 0.000
Dmean (Gy) 3.57 ± 1.81 3.42 ± 1.74 9.251 0.000
Heart in left-sided patients supine
Dmean (Gy) 5.38 ± 2.07 5.29 ± 2.06 4.752 0.000
V5 (%) 16.18 ± 6.46 15.88 ± 6.38 4.364 0.001
V10 (%) 11.98 ± 5.60 11.90 ± 5.60 3.294 0.006
V20 (%) 9.70 ± 5.06 9.65 ± 5.09 2.270 0.041
V30 (%) 7.94 ± 4.53 7.89 ± 4.54 2.876 0.013
V40 (%) 2.88 ± 1.91 2.33 ± 1.75 4.125 0.001
Prone
Dmean (Gy) 5.20 ± 2.30 5.04 ± 2.26 4.734 0.000
V5 (%) 18.10 ± 9.00 17.71 ± 8.91 5.498 0.000
V10 (%) 13.34 ± 8.21 13.18 ± 8.16 4.112 0.000
V20 (%) 9.10 ± 5.67 8.88 ± 5.57 3.231 0.003
V30 (%) 5.06 ± 3.69 4.91 ± 3.62 4.380 0.001
V40 (%) 2.22 ± 2.09 1.73 ± 1.75 2.902 0.012

SIB simultaneous integrated boost, SEB sequential integrated boost, HFWBI hypofractionated whole-breast irradiation, V5 the volumes that received ≥ 5 Gy, V10 the volumes that received ≥ 10 Gy, V20 the volumes that received ≥ 20 Gy, V30 the volumes that received ≥ 30 Gy, V40 the volumes that received ≥ 40 Gy, Dmean the mean dose.